Nordmann News & Events News Excipients for pharmaceutical and supplement capsules
28 January 2025

Excipients for pharmaceutical and supplement capsules

Nordmann partner IOI Oleo is a trusted partner in pharmaceuticals and nutrition, leveraging its expertise to offer a comprehensive selection of capsule ingredients that satisfy the highest regulatory standards. IOI Oleo products strike a perfect balance between naturalness, efficacy, multifunctionality, and conformity, making them perfect for creating ingredient-reduced and consistent formulations. The company’s capsule ingredients are suitable for a wide range of applications that includes functional foods, nutritional supplements (diet foods), nutraceuticals, pharmaceutical dosage forms and products for special diets and/or metabolic disorders. 

Superior quality

With two production facilities in Germany, IOI Oleo is the leading supplier of medium-chain triglycerides (MCT) and associated products in Europe. Whether developing medicinal capsules or dietary supplements, the company prioritizes the health and well-being of consumers. This commitment drives IOI Oleo’s efforts to ensure the highest quality in everything it produces.

A woman in an orange sweater is holding a pill in her hand

Capsules are one of the most popular dosage forms

After tablets, capsules are the second most popular dosage form among consumers. Experts predict, however, that the market for capsules will continue to see double-digit growth rates over the next decade.

Their popularity is no surprise, given their numerous advantages. Consumers appreciate how easy capsules are to take, for example, and that they help avoid the often unpleasant taste of active ingredients or excipients.

Capsules are a game-changer for developers, too, and during production. They are easy to dose, precise, cheap to make, and long-lasting – and they save space. They also allow for sensitive ingredients to be processed gently. 

There are three different types of capsules: hard, soft, and chewable. 

Focusing on essential ingredients

As more and more products are being developed with simple formulas, capsule manufacturers are focusing on the ingredients that are needed to deliver active ingredients most effectively. IOI Oleo’s portfolio includes a range of new, functional lipids that can be used in all types of capsules while delivering: 

 

  • a wide range of properties and textures
  • nutritional benefits linked to the unique metabolic processes associated with medium-chain lipids
  • plant-based origins
  • effective mitigation of the poor solubility of active ingredients in BCS classes II and IV, allowing them to be successfully administered through special drug delivery systems like SEDDS
     
PRODUCT

COMPENDIAL TITLE/ 

CHEMICAL DESCRIPTION

PRIMARY SCOPE
OF USE
MELTING
POINT
CONSISTENCY
AT ROOM TEMPERATURE
MONOESTER
CONTENT (%)
HYDROXYL VALUE
(MG KOH/G)
FUNCTION

 

SOFTISAN® 378

Hard FatPharma~ 39soft-creamy paste< 1< 50Carrier
IMWITOR® 308 Glycerol monocaprylate, type IIPharma27-33solid> 80450 - 550Carrier, Solubilizer & Bio-availibility booster
IMWITOR® 742Glycerol monocaprylocaprate, type I (available with CEP support)Pharma~ 25pasty to solid45 - 75315 - 380Carrier, Solubilizer & Bio-availibility booster
IMWITOR® 988Glycerol monocaprylate, type IPharma~ 23liquid45 - 75315 - 380Carrier, Solubilizer & Bio-availibility booster
MIGLYOL® 812 NTriglycerides, medium-chainPharma< 0liquid< 1<10Carrier, Lubricant
MIGLYOL® 810 NTriglycerides, medium-chainPharma< 0liquid< 1<10Carrier, Lubricant
WITARIX® MCT 60/40Caprylic/Capric triglycerideNutraceutical< 0liquid< 0<10Carrier, Glazing and release agent, Lubricant
WITARIX® MCT 70/30Caprylic/Capric triglycerideNutraceutical< 0liquid< 0<10Carrier, Glazing and release agent, Lubricant
WITARIX® MCT C8Caprylic triglycerideNutraceutical< 0liquid< 0<10 Carrier, Glazing and release agent, Lubricant
WITARIX® MCT powder AC8CNCaprylic triglyceride and gum acaciaNutraceutical< 0powder< 0<10Solution for an easy-to-handle powder, with a high oil load and good solubility

The capsule ingredients from IOI Oleo demonstrate both market-leading stability (Rancimat test and conductivity measurement) and polarity (suitability for formulation).

Bioavailability

IOI Oleo’s medium-chain partial glycerides (MCPGs) and triglycerides (MCTs) are characterized by a number of key properties that make them important as carriers and bioavailability-enhancers in nutraceutical and pharmaceutical applications. These include solubility, excellent permeability and transport, particle dispersion, rapid absorption, versatility, compatibility, taste and odor neutrality, safety and metabolization.

Active substances

Active ingredients such as hormones, cannabinoids, protease inhibitors, alpha-blockers, androgen blockers, tyrosine kinase inhibitors, vitamins and vitamin derivatives can all be supplied in capsules using IOI Oleo excipients.

Sustainability

IOI Oleo has established a vision to lead the way in both the production and procurement of sustainable palm oil. 

The company is committed to cultivating sustainable oil palm plantations and implementing a responsible global palm oil supply chain. 

This includes the basic availability of all palm oil-based specialties in RSPO M/B quality. 

For more information, please contact:

Dr. Claudia Heling
Dr. Claudia Heling
Senior Technical Sales & Product Manager | Health Care
Nordmann, Rassmann GmbH

Distributed in:

Austria, Bosnia-Herzegovina, Croatia, the Czech Republic, Germany, Hungary, the Nordic countries, Poland, Slovakia and Slovenia.

IOI Ole logo in black letters

Related news

28 January 2025

Excipients for pharmaceutical and supplement capsules

Nordmann partner IOI Oleo is a trusted partner in pharmaceuticals and nutrition, leveraging its expertise to offer a comprehensive selection of capsule ingredients that satisfy the highest regulatory standards. IOI Oleo products strike a perfect balance between naturalness, efficacy, multifunctionality, and conformity, making them perfect for creating ingredient-reduced and consistent formulations. The company’s capsule ingredients are suitable for a wide range of applications that includes functional foods, nutritional supplements (diet foods), nutraceuticals, pharmaceutical dosage forms and products for special diets and/or metabolic disorders. 
SPOTLIGHT ON SUSTAINABILITY
4 November 2024

Botanical extracts from new partner Ransom Naturals Ltd.

Nordmann is pleased to announce the start of a new partnership with Ransom Naturals Ltd. (RNL) in BeNeLux, DACH, Nordic and Poland. In addition to being one of Europe’s leading GMP-accredited developers and manufacturers of active pharmaceutical ingredients (API) for the pharmaceutical industry, RNL is a renowned specialist in the production of botanical extracts for use in food and beverages.
SPOTLIGHT ON SUSTAINABILITY
9 September 2024

Delicious and nutritious – for every meal!

Nordmann partner Rabeler Fruchtchips is proud to announce the launch of a new product: mango fruit powder with organic sunflower protein. This high-quality, roller-dried ingredient is made from organic mango puree blended with organic sunflower protein, featuring 70% fruit content.
×
Sign up for our newsletter!
Subscribe to our newsletter and get exclusive quarterly updates.